A multiparametric score for assessing the individual risk of severe Covid-19 among patients with Multiple Sclerosis.

ABSTRACT:

Background

Many risk factors for the development of severe forms of Covid-19 have been identified, some applying to the general population and others specific to Multiple Sclerosis (MS) patients. However, a score for quantifying the individual risk of severe Covid-19 in patients with MS is not available. The aim of this study was to construct such score and to evaluate its performance.

Methods

Data on patients with MS infected with Covid-19 in Italy, Turkey and South America were extracted from the Musc-19 platform. After imputation of missing values, data were separated into training data set (70%) and validation data set (30%). Univariable logistic regression models were performed in the training dataset to identify the main risk factors to be included in the multivariable

SUBMITTER: Ponzano M 

PROVIDER: S-EPMC9130313 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature