Quantifying the intensity of adverse events with ibuprofen and oxycodone: an observational cohort study.

ABSTRACT:

Objective

To quantify the frequency and intensity of adverse events (AEs), commonly known as side effects, experienced by children receiving either ibuprofen or oxycodone for pain management following an acute fracture. Secondary objectives were to quantify functional outcome impairment and describe demographic and clinical characteristics associated with AEs.

Design

Observational cohort study.

Setting

Paediatric emergency department.

Patients

Patients (n=240) aged 4-16 years diagnosed with an acute fracture.

Intervention

Prescribed either ibuprofen (n=179) or oxycodone (n=61) for pain.

Main outcome measures

Families were called for the first 3 days after discharge to report the presence and intensity of AEs and their child's functional outcomes (

SUBMITTER: Ali S 

PROVIDER: S-EPMC9131055 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature