Magnetoencephalography Imaging Reveals Abnormal Information Flow in Temporal Lobe Epilepsy.

ABSTRACT: Background/Introduction: Widespread network disruption has been hypothesized to be an important predictor of outcomes in patients with refractory temporal lobe epilepsy (TLE). Most studies examining functional network disruption in epilepsy have largely focused on the symmetric bidirectional metrics of the strength of network connections. However, a more complete description of network dysfunction impacts in epilepsy requires an investigation of the potentially more sensitive directional metrics of information flow. Methods: This study describes a whole-brain magnetoencephalography-imaging approach to examine resting-state directional information flow networks, quantified by phase-transfer entropy (PTE), in patients with TLE compared with healthy controls (HCs).

SUBMITTER: Kudo K 

PROVIDER: S-EPMC9131359 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature