Clinical outcomes and visual prognostic factors in congenital aniridia.

ABSTRACT:

Background

Evaluate outcomes and identify prognostic factors in congenital aniridia.

Methods

Retrospective interventional case series of patients with congenital aniridia treated between 2012-2020. Ocular examination and surgical details were collected. Surgical failure was defined as disease progression or need for additional surgery for same/related indication. Kaplan-Meier survival curves, Wilcoxon test, and univariate and multivariate linear regression analyses were performed.

Results

Ninety-four patients with congenital aniridia presented at median 19.0 years. Two-thirds of patients underwent ≥ 1intraocular surgery, with average of 1.7 ± 2.3 surgeries/eye. At final follow-up (median 4.0 years), 45% of eyes had undergone lensectomy. Aphakic eyes showed worse visua

SUBMITTER: Jacobson A 

PROVIDER: S-EPMC9131660 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature