Prospective association between dietary pesticide exposure profiles and type 2 diabetes risk in the NutriNet-Sante cohort.

ABSTRACT:

Background

Studies focusing on dietary pesticides in population-based samples are scarce and little is known about potential mixture effects. We aimed to assess associations between dietary pesticide exposure profiles and Type 2 Diabetes (T2D) among NutriNet-Santé cohort participants.

Methods

Participants completed a Food Frequency Questionnaire at baseline, assessing conventional and organic food consumption. Exposures to 25 active substances used in European Union pesticides were estimated using the Chemisches und Veterinäruntersuchungsamt Stuttgart residue database accounting for farming practices. T2D were identified through several sources. Exposure profiles were established using Non-Negative Matrix Factorization (NMF), adapted for sparse data. Cox models adjusted for

SUBMITTER: Rebouillat P 

PROVIDER: S-EPMC9131692 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature