Analysis of Neuropsychiatric Diagnoses After Montelukast Initiation.

ABSTRACT:

Importance

The evidence base for the association between montelukast and adverse neuropsychiatric outcomes is mixed and inconclusive. Several methodological limitations have been identified in the evidence base on the safety of montelukast in observational studies.

Objective

To investigate the association between new montelukast exposure and 1-year incident neuropsychiatric diagnoses with improved precision and control for baseline confounders.

Design, setting, and participants

This propensity score-matched cohort study was conducted using electronic health records from 2015 to 2019 in the TriNetX Analytics Network patient repository of more than 51 million patients from 56 health care organizations, mainly in the US. Included patients were those aged 15 to 64 years a

SUBMITTER: Paljarvi T 

PROVIDER: S-EPMC9131741 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature