The Use of MALDI-TOF MS as a Diagnostic Tool for Adult Trichuris Species.

ABSTRACT: Trichuriasis is considered a neglected tropical disease, being the second most common helminthiasis in humans. Detection of Trichuris in routine diagnosis is usually done by microscopic detection of eggs in fecal samples. Other molecular analyses are more reliable and could be used, but these analyses are not routinely available in clinical microbiology laboratories. The use of matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) mass spectrometry (MS) is increasing since the last decades due to its recent evidence as a potential role for reliable identification of microorganisms and a few nematodes. But, for parasites detection, normalized protocols and the acquisition and introduction of new species to the database are required. We carried out a preliminary study

SUBMITTER: Rivero J 

PROVIDER: S-EPMC9132177 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature