Vascular endothelial growth factor levels in tuberculosis: A systematic review and meta-analysis.

ABSTRACT:

Background

Changes in endothelial function are implicated in the spread of tuberculosis (TB). Studies suggest a role for the vascular endothelial growth factor (VEGF) in TB-related endothelial function changes. However, the findings of studies investigating the VGEF profile in TB are not consistent, and no formal systematic review and meta-analysis exists summarizing these studies.

Methods

We did a meta-analysis of studies assessing VEGF levels in patients with TB. A systematic search on June 25, 2021, was conducted for eligible studies that made VEGF measurements in an unstimulated sample, e.g., a blood fraction (plasma or serum), cerebrospinal fluid (CSF), pleural effusion (PE), or bronchoalveolar lavage fluid, and ascites or pericardial fluid for patients with TB and cont

SUBMITTER: Saghazadeh A 

PROVIDER: S-EPMC9132289 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature