Long-term metabolic fate and mortality in obesity without metabolic syndrome.

ABSTRACT:

Background

Obesity and metabolic syndrome (MetS) are known to expose to atrial fibrillation (AF), cardiovascular diseases (CVD) and mortality. Metabolically healthy obesity refers to obesity without MetS. This study aimed to investigate how obesity and MetS modify the risk of CVD, AF and mortality in very long-time follow-up.

Methods

Finnish middle-aged subjects (n = 1045) were grouped into four subgroups according to the presence of obesity and MetS. CVD events and AF were followed for 24 years and total mortality for 30 years. Moreover, 600 available patients had a follow-up visit for metabolic examinations after approximately 22 years.

Results

One-hundred and sixty-two (30%) subjects without obesity or MetS died during the follow-up. Ninety-two (17%) of the

SUBMITTER: Karajamaki AJ 

PROVIDER: S-EPMC9132486 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature