Development and application of a health-based framework for informing regulatory action in relation to exposure of microplastic particles in California drinking water.

ABSTRACT: Microplastics have been documented in drinking water, but their effects on human health from ingestion, or the concentrations at which those effects begin to manifest, are not established. Here, we report on the outcome of a virtual expert workshop conducted between October 2020 and October 2021 in which a comprehensive review of mammalian hazard studies was conducted. A key objective of this assessment was to evaluate the feasibility and confidence in deriving a human health-based threshold value to inform development of the State of California's monitoring and management strategy for microplastics in drinking water. A tiered approach was adopted to evaluate the quality and reliability of studies identified from a review of the peer-reviewed scientific literature. A total of 41 in vitro a

SUBMITTER: Coffin S 

PROVIDER: S-EPMC9132802 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature