An exposome-wide association study on body mass index in adolescents using the National Health and Nutrition Examination Survey (NHANES) 2003-2004 and 2013-2014 data.

ABSTRACT: Excess weight is a public health challenge affecting millions worldwide, including younger age groups. The human exposome concept presents a novel opportunity to comprehensively characterize all non-genetic disease determinants at susceptible time windows. This study aimed to describe the association between multiple lifestyle and clinical exposures and body mass index (BMI) in adolescents using the exposome framework. We conducted an exposome-wide association (ExWAS) study using U.S. National Health and Nutrition Examination Survey (NHANES) 2003-2004 wave for discovery of associations between study population characteristics and zBMI, and used the 2013-2014 wave to replicate analysis. We included non-diabetic and non-pregnant adolescents aged 12-18 years. We performed univariable and mult

SUBMITTER: Haddad N 

PROVIDER: S-EPMC9132896 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature