Prediction and prevention of preterm birth in pregnant women living with HIV on antiretroviral therapy.

ABSTRACT:

Introduction

The rate of spontaneous preterm-birth among pregnant women living with HIV on antiretroviral therapy (ART) is 3- to 4-fold higher when compared to HIV-negative women. The pathophysiology of preterm-birth related to HIV or ART remains unknown, especially as women living with HIV are often excluded from preterm birth studies.

Areas covered

This review discusses the currently available evidence on the prediction and prevention of preterm-birth in pregnant women living with HIV. A review of the literature was conducted of primary articles between 2005 and 2021 measuring the association or lack thereof between combination ART and preterm birth, as well as of other predisposing factors to preterm birth in women living with HIV, including cervical length, vaginal micro

SUBMITTER: Jones AJ 

PROVIDER: S-EPMC9133156 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature