Relationships between serum iron and liver diseases in nutrition intervention trials: A nested case-control study.

ABSTRACT:

Background

Serum iron is associated with the risk of several diseases. However, limited prospective studies have been performed between serum iron and the subsequent risk of chronic liver disease (CLD) and primary liver cancer (PLC) incidence.

Methods

We performed a nested case-control study using data from the Linxian Nutrition Intervention Trials among participants who developed PLC incidence or died from CLD over 22-years of follow-up. We calculated the odds ratios (ORs) and 95% confidence intervals (CIs) to estimate the risk of PLC incidence or CLD death in different quintile of baseline serum iron using logistic regression.

Results

Individuals with serum iron in the highest quintile, compared to those in the second quintile (the reference), had an increased risk

SUBMITTER: Liu Y 

PROVIDER: S-EPMC9133189 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature