Effect of Hyaluronate Acid Injection on Dose-Volume Parameters in Brachytherapy for Cervical Cancer.

ABSTRACT:

Purpose

Hyaluronate gel has been injected as a spacer into the rectovaginal fossa and vesicouterine fossa during brachytherapy for patients with cervical cancer at our institution. The effect of hyaluronate gel injection (HGI) on dose-volume parameters was investigated in this study.

Methods and materials

Between July 2008 to January 2020, a total of 104 patients (non-HGI group: 52 patients; HGI group: 52 patients) who underwent curative radiation therapy for cervical cancer were selected. The total doses of external beam radiation therapy and brachytherapy for high-risk clinical target volume (CTV_HR) D₉₀, bladder D_2cc, and rectal D_2cc were converted to the equivalent dose in 2 Gy fractions (EQD2) and were analyzed for association

SUBMITTER: Kobayashi R 

PROVIDER: S-EPMC9133393 | biostudies-literature | 2022 May-Jun

REPOSITORIES: biostudies-literature