Test Performance of Cervical Cytology Among Adults With vs Without Human Papillomavirus Vaccination.

ABSTRACT:

Importance

Current US cervical cancer screening guidelines do not differ by human papillomavirus (HPV) vaccination status. However, as the positive predictive value (PPV) of a screening test decreases, the risk of a false-positive result increases.

Objective

To evaluate whether HPV vaccination is associated with decreased PPV for abnormal cervical cytology.

Design, setting, and participants

This retrospective cohort study conducted via electronic medical record review included eligible patients aged 21 to 35 years who had at least 1 cervical cytology result within a single health system between January 2015 and December 2018. The health system comprises a partnership between an academic health center and a private not-for-profit health center. Patients with abnormal s

SUBMITTER: Teoh D 

PROVIDER: S-EPMC9133945 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature