Quantifying the impact of mass vaccination programmes on notified cases in the Netherlands.

ABSTRACT: Vaccination programmes are considered a main contributor to the decline of infectious diseases over the 20th century. In recent years, the national vaccination coverage in the Netherlands has been declining, highlighting the need for continuous monitoring and evaluation of vaccination programmes. Our aim was to quantify the impact of long-standing vaccination programmes on notified cases in the Netherlands. We collected and digitised previously unavailable monthly case notifications of diphtheria, poliomyelitis, mumps and rubella in the Netherlands over the period 1919-2015. Poisson regression models accounting for seasonality, multi-year cycles, secular trends and auto-correlation were fit to pre-vaccination periods. Cases averted were calculated as the difference between observed and exp

SUBMITTER: van Wijhe M 

PROVIDER: S-EPMC9134361 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature