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Highly Efficient Industrial Dye Degradation, Bactericidal Properties, and In Silico Molecular Docking Analysis of Ag/Cellulose-Doped CuO Nanostructures.


ABSTRACT: In this research, CuO nanostructures doped with Ag and cellulose nanocrystals (CNC) were synthesized using a facile coprecipitation technique. In this work, we doped Ag into fixed quantities of CNC and CuO to improve the photocatalytic, catalytic, and antibacterial activity. It was noted that catalytic activity increased upon doping, which was attributed to the formation of nanorods and a pH effect, while the reverse trend was observed in photocatalytic activity. The addition of Ag and CNC dopants into CuO improved the bactericidal efficacy for S. aureus and E. coli. In addition, to obtain insight into the possible mechanism behind their biocidal effects, molecular docking studies were conducted against specific enzyme targets: namely, dihydrofolate reductase from E. coli and DNA gyrase from S. aureus. This study suggested that codoped CuO could be highly efficient in the cleaning of polluted water and antibacterial applications.

SUBMITTER: Ikram M 

PROVIDER: S-EPMC9134382 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature

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Highly Efficient Industrial Dye Degradation, Bactericidal Properties, and <i>In Silico</i> Molecular Docking Analysis of Ag/Cellulose-Doped CuO Nanostructures.

Ikram Muhammad M   Hafeez Izan I   Naz Misbah M   Haider Ali A   Naz Sadia S   Ul-Hamid Anwar A   Haider Junaid J   Shahzadi Anum A   Imran Muhammad M   Nabgan Walid W   Ali Salamat S  

ACS omega 20220509 20


In this research, CuO nanostructures doped with Ag and cellulose nanocrystals (CNC) were synthesized using a facile coprecipitation technique. In this work, we doped Ag into fixed quantities of CNC and CuO to improve the photocatalytic, catalytic, and antibacterial activity. It was noted that catalytic activity increased upon doping, which was attributed to the formation of nanorods and a pH effect, while the reverse trend was observed in photocatalytic activity. The addition of Ag and CNC dopan  ...[more]

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