Pressor therapy in acute ischaemic stroke: an updated systematic review.

ABSTRACT:

Background

Low blood pressure (BP) in acute ischaemic stroke (AIS) is associated with poor functional outcome, death, or severe disability. Increasing BP might benefit patients with post-stroke hypotension including those with potentially salvageable ischaemic penumbra. This updated systematic review considers the present evidence regarding the use of vasopressors in AIS.

Methods

We searched the Cochrane Database of Systematic Reviews, MEDLINE, EMBASE and trial databases using a structured search strategy. We examined reference lists of relevant publications for additional studies examining BP elevation in AIS.

Results

We included 27 studies involving 1886 patients. Nine studies assessed increasing BP during acute reperfusion therapy (intravenous thrombolysis, mechani

SUBMITTER: Stromsnes TA 

PROVIDER: S-EPMC9134777 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature