Associations of Blautia Genus With Early-Life Events and Later Phenotype in the NutriHS.

ABSTRACT:

Introduction

Early-life events are associated with the risk of obesity and comorbidities later in life. The gut microbiota-whose composition is influenced by genetics and environmental factors-could be involved. Since the microbiota affects metabolism and fat storage, early-life insults could contribute to the occurrence of obesity driven, in part, by microbiota composition. We examined associations of gut bacteria with early-life events, nutritional status, and body composition in the Nutritionist's Health Study (NutriHS).

Methods

A cross-sectional study of 114 female participants examining early-life data, body composition, and biological samples was conducted. Fecal microbiota structure was determined targeting the V4 region of the 16S rRNA gene. Principal coordinates ana

SUBMITTER: Freitas RGBON 

PROVIDER: S-EPMC9134825 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature