Incidence of chikungunya virus infections among Kenyan children with neurological disease, 2014-2018: A cohort study.

ABSTRACT:

Background

Neurological complications due to chikungunya virus (CHIKV) infection have been described in different parts of the world, with children being disproportionately affected. However, the burden of CHIKV-associated neurological disease in Africa is currently unknown and given the lack of diagnostic facilities in routine care it is possible that CHIKV is an unrecognized etiology among children with encephalitis or other neurological illness.

Methods and findings

We estimated the incidence of CHIKV infection among children hospitalized with neurological disease in Kilifi County, coastal Kenya. We used reverse transcriptase polymerase chain reaction (RT-PCR) to systematically test for CHIKV in cerebrospinal fluid (CSF) samples from children aged <16 years hospitalized w

SUBMITTER: Nyamwaya DK 

PROVIDER: S-EPMC9135332 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature