Occurrence and transmission potential of asymptomatic and presymptomatic SARS-CoV-2 infections: Update of a living systematic review and meta-analysis.

ABSTRACT:

Background

Debate about the level of asymptomatic Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection continues. The amount of evidence is increasing and study designs have changed over time. We updated a living systematic review to address 3 questions: (1) Among people who become infected with SARS-CoV-2, what proportion does not experience symptoms at all during their infection? (2) What is the infectiousness of asymptomatic and presymptomatic, compared with symptomatic, SARS-CoV-2 infection? (3) What proportion of SARS-CoV-2 transmission in a population is accounted for by people who are asymptomatic or presymptomatic?

Methods and findings

The protocol was first published on 1 April 2020 and last updated on 18 June 2021. We searched PubMed, Embase, bioR

SUBMITTER: Buitrago-Garcia D 

PROVIDER: S-EPMC9135333 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature