Different Frequency Bands in Various Regions of the Brain Play Different Roles in the Onset and Wake-Sleep Stages of Infantile Spasms.

ABSTRACT:

Objective

The study aimed to identify the signatures of brain networks using electroencephalogram (EEG) in patients with infantile spasms (IS).

Methods

Scalp EEGs of subjects with IS were prospectively collected in the first year of life (n = 8; age range 4-8 months; 3 males, 5 females). Ten minutes of ictal and interictal EEGs were clipped and filtered into different EEG frequency bands. The values of each pair of EEG channels were directly compared between ictal with interictal onsets and the sleep-wake phase to calculate IS brain network attributes: characteristic path length (CPL), node degree (ND), clustering coefficient (CC), and betweenness centrality (BC).

Results

CPL, ND, and CC of the fast waves decreased while BC increased. CPL and BC of the slow wav

SUBMITTER: Dong Y 

PROVIDER: S-EPMC9135356 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature