Comparison of disc and wire electrodes to restore cough via lower thoracic spinal cord stimulation.

ABSTRACT:

Objective

To compare the safety and effectiveness of wire (WE) vs. disc (DE) electrodes to restore cough in subjects with spinal cord injury (SCI).

Design

Clinical trials assessing the effectiveness and clinical outcomes associated with two electrode systems to activate the expiratory muscles.

Setting

Inpatient hospital setting for DE or WE electrode insertion; outpatient evaluation of cough efficacy and instructions for home use.

Participants

Twenty-nine subjects with SCI; 17 participants with DE and 12 with WE implants.

Intervention

Surgical implantation of WE or DE to restore cough. Daily application of spinal cord stimulation (SCS) at home.

Main outcome measure(s)

Airway pressure (P) and peak airflow (F) generation achieved with SCS; clinical

SUBMITTER: DiMarco AF 

PROVIDER: S-EPMC9135439 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature