Dataset Information

Therapeutic effectiveness of tuberculous aneurysm and risk factors for mortality: a systematic review.

ABSTRACT:

Objective

This study aimed to determine the therapeutic effectiveness of tuberculous aortic aneurysms (TBAAs) and the risk factors for mortality.

Methods

We reviewed all case reports of TBAAs treated with open surgery or endovascular aneurysm repair (EVAR) from online database in 1996-2021. Only thoracic and abdominal aortic aneurysms were included.

Results

Eighty cases of open surgery and 42 cases of EVAR were included. The 2-year mortality and perioperative mortality rates of open surgery were 11.3% and 10.0%, respectively. Emergent open surgery had a significantly higher mortality (25.0%) than non-emergent open surgery (6.7%). In the EVAR group, 2-year mortality, perioperative mortality, and TBAA-related mortality were 16.7%, 4.8%, and 10.0%, respectively. Patients with typical tuberculosis (TB) symptoms before EVAR had a significantly higher TBAA-related mortality (35.0%) than patients with no typical TB symptoms before EVAR (0%). In the open surgery group, the rate of TB recurrence (2.7% vs 2.4%) and aneurysm recurrence (8.1% vs 7.3%) were quite close between preoperative anti-TB-treated and postoperative anti-TB-treated cases. However, in the EVAR group, TB recurrence (8.7% vs 0%) and aneurysm recurrence (12.5% vs 6.25%) were more common in postoperative anti-TB-treated cases.

Conclusion

Open surgery was accompanied by higher perioperative mortality, whereas EVAR was followed with higher TBAA-related mortality. Emergent surgical choices of open surgery may be associated with high perioperative mortality. Typical TB symptoms before EVAR are a significant risk factor for mortality after EVAR. Early anti-TB treatment should be administered if EVAR is the surgical option.

SUBMITTER: Yi S

PROVIDER: S-EPMC9135858 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature

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Publications

Therapeutic effectiveness of tuberculous aneurysm and risk factors for mortality: a systematic review.

Yi Shengwu S Sheng Lingjie L Li Wei W

General thoracic and cardiovascular surgery 20220404 6

<h4>Objective</h4>This study aimed to determine the therapeutic effectiveness of tuberculous aortic aneurysms (TBAAs) and the risk factors for mortality.<h4>Methods</h4>We reviewed all case reports of TBAAs treated with open surgery or endovascular aneurysm repair (EVAR) from online database in 1996-2021. Only thoracic and abdominal aortic aneurysms were included.<h4>Results</h4>Eighty cases of open surgery and 42 cases of EVAR were included. The 2-year mortality and perioperative mortality rate ...[more]

PMID: 35378674

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Dataset Information

Therapeutic effectiveness of tuberculous aneurysm and risk factors for mortality: a systematic review.

Objective

Methods

Results

Conclusion

Publications

Therapeutic effectiveness of tuberculous aneurysm and risk factors for mortality: a systematic review.

Similar Datasets

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