Enantioseparation in Hierarchically Porous Assemblies of Homochiral Cages.

ABSTRACT: Efficient enantioselective separation using porous materials requires tailored and diverse pore environments to interact with chiral substrates; yet, current cage materials usually feature uniform pores. Herein, we report two porous assemblies, PCC-60 and PCC-67, using isostructural octahedral cages with intrinsic microporous cavities of 1.5 nm. The PCC-67 adopts a densely packed mode, while the PCC-60 is a hierarchically porous assembly featuring interconnected 2.4 nm mesopores. Compared with PCC-67, the PCC-60 demonstrates excellent enantioselectivity and recyclability in separating racemic diols and amides. This solid adsorbent PCC-60 is further utilized as a chiral stationary phase for high-performance liquid chromatography (HPLC), enabl

SUBMITTER: Zhu C 

PROVIDER: S-EPMC9136985 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature