Absence of Consistent Sex Differences in Outcomes From Symptomatic Carotid Endarterectomy and Stenting Randomized Trials.

ABSTRACT:

Background and purpose

CREST (Carotid Revascularization Endarterectomy Versus Stenting Trial) reported a higher periprocedural risk for any stroke, death, or myocardial infarction for women randomized to carotid artery stenting (CAS) compared with women randomized to carotid endarterectomy (CEA). No difference in risk by treatment was detected for women relative to men in the 4-year primary outcome. We aimed to conduct a pooled analysis among symptomatic patients in large randomized trials to provide more precise estimates of sex differences in the CAS-to-CEA risk for any stroke or death during the 120-day periprocedural period and ipsilateral stroke thereafter.

Methods

Data from the Carotid Stenosis Trialists' Collaboration included outcomes from symptomatic patients in EVA

SUBMITTER: Howard VJ 

PROVIDER: S-EPMC9136999 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature