Development of multivariable models to predict perinatal depression before and after delivery using patient reported survey responses at weeks 4-10 of pregnancy.

ABSTRACT:

Background

Perinatal depression is estimated to affect ~ 12% of pregnancies and is linked to numerous negative outcomes. There is currently no model to predict perinatal depression at multiple time-points during and after pregnancy using variables ascertained early into pregnancy.

Methods

A prospective cohort design where 858 participants filled in a baseline self-reported survey at week 4-10 of pregnancy (that included social economics, health history, various psychiatric measures), with follow-up until 3 months after delivery. Our primary outcome was an Edinburgh Postnatal Depression Score (EPDS) score of 12 or more (a proxy for perinatal depression) assessed during each trimester and again at two time periods after delivery. Five gradient boosting machines were trained to

SUBMITTER: Reps JM 

PROVIDER: S-EPMC9137134 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature