NDM-5-Producing Escherichia coli Co-Harboring mcr-1 Gene in Companion Animals in China.

ABSTRACT: Carbapenem and colistin are important antibiotics for the treatment of infections caused by multidrug-resistant Gram-negative pathogens. Here, we isolated the bla_NDM-5-harboring Escherichia coli in companion animals in healthy or diseased companion animals from veterinary clinics in six cities in China from July to November 2016. A total of 129 rectal swabs of healthy or diseased dogs and cats were collected from veterinary clinics in six different cities in China, and the isolates were subjected to carbapenem and colistin susceptibility testing. Resistance genes were confirmed using PCR. Conjugation experiments were conducted to determine the transferability of antibiotic resistance genes (ARGs) in the strains. The isolated rate of bla_NDM-5-harbo

SUBMITTER: Kuang X 

PROVIDER: S-EPMC9137672 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature