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Sleep and Executive Functioning in Pediatric Traumatic Brain Injury Survivors after Critical Care.


ABSTRACT: Over 50,000 children are hospitalized annually for traumatic brain injury (TBI) and face long-term cognitive morbidity. Over 50% develop sleep/wake disturbances (SWDs) that can affect brain development and healing. We hypothesized SWDs would portend worse executive function outcomes in children aged 3-18 years with TBI 1-3 months after hospital discharge. SWDs were defined using the Sleep Disturbances Scale for Children (t-scores ≥ 60). Outcomes included the Global Executive Composite (GEC, t-score) from the Behavior Rating Inventory of Executive Function, Second and Preschool Editions, and multiple objective executive function assessments combined through Principal Components Analysis into a Neurocognitive Index (NCI, z-score). Multiple linear regression evaluated associations between SWD

SUBMITTER: Williams CN 

PROVIDER: S-EPMC9139390 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature