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Integrative Modeling and Visualization of Exosomes.


ABSTRACT: Information from proteomics, microscopy, and structural biology are integrated to create structural models of exosomes, small vesicles released from cells. Three visualization methods are employed and compared: 2D painting of a cross section using traditional media, manual creation of a cross section using the mesoscale 2.5D digital painting software cellPAINT, and generation of a 3D atomic model using the mesoscale modeling program cellPACK.

SUBMITTER: Jimenez J 

PROVIDER: S-EPMC9139774 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Integrative Modeling and Visualization of Exosomes.

Jiménez Julia J   Autin Ludovic L   Ibáñez de Cáceres Inmaculada I   Goodsell David S DS  

The Journal of biocommunication 20191127 2


Information from proteomics, microscopy, and structural biology are integrated to create structural models of exosomes, small vesicles released from cells. Three visualization methods are employed and compared: 2D painting of a cross section using traditional media, manual creation of a cross section using the mesoscale 2.5D digital painting software cellPAINT, and generation of a 3D atomic model using the mesoscale modeling program cellPACK. ...[more]

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