Outcomes of Kidney Transplantation in Patients with Autosomal Dominant Polycystic Kidney Disease: Our Experience Based on 35-Years Follow-Up.

ABSTRACT:

Background and objectives

For patients with end-stage renal disease (ESRD), the best replacement therapy is renal transplant (RTx) to ensure life with good quality. Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder and a common cause of ESRD. Different from ESRD of other causes, ADPKD patients need careful pre-RTx evaluations like detecting the presence of intracranial aneurisms, cardiac manifestations, and complications of liver and renal cysts.

Materials

We retrieved a total of 1327 RTx patients receiving 1382 times RTx (two recipients with three times, 48 recipients with two times) over the last 35 years. Only 41 of these patients were diagnosed with ADPKD.

Results

At the first RTx, patients' ages were 42.9 ± 12.6 (mean ± SD) years. Ages of

SUBMITTER: Tsai TY 

PROVIDER: S-EPMC9139921 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature