Relative tumor volume has prognostic relevance in canine sinonasal tumors treated with radiation therapy: A retrospective study.

ABSTRACT: Tumor volume is controversially discussed as a prognostic factor in dogs treated with radiation therapy for sinonasal tumors. Dogs' body sizes vary widely and relative rather than absolute tumor volume might provide better prognostic information. Our hypothesis was that relative rather than absolute tumor volume (gross tumor volume, GTV) influences time to progression (TTP) and that a larger tumor volume is correlated with a higher tumor stage. We retrospectively investigated possible correlations of initial GTV to weight, body surface area (BSA), nasal cavity size and the tumor stage in 49 dogs with sinonasal tumors. Here, also presumed sinonasal tumors, esthesioneuroblastomas and histologically benign tumors were included. The possible impact of absolute and relative GTV on response and

SUBMITTER: Czichon F 

PROVIDER: S-EPMC9140277 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature