Dataset Information

Lessons We Have Learned Regarding Seroprevalence in High and Low SARS-CoV-2 Contexts in Greece before the Omicron Pandemic Wave.

ABSTRACT:

Background

Antibody seroprevalence in rural communities remains poorly investigated. We compared the SARS-CoV-2 seroprevalence in two Greek communities in June and July 2021 after the end of the Delta-driven pandemic wave that started in November 2020. One community was affected worse than the other.

Methods

The SARS-CoV-2 IgG II Quant method (Architect, Abbott, IL, USA) was used for antibody testing.

Results

We found a high rate of SARS-CoV-2 seropositivity in both communities, approaching 77.5%. In the area with a higher burden of COVID-19, Malesina, seropositivity was achieved with vaccine-acquired and naturally acquired immunity, whereas in the low-burden context of Domokos, the high rates of seropositivity were achieved mainly with vaccination. Previously infected individuals were less likely to be vaccinated than previously uninfected adults. The antibody titers were significantly higher in previously infected, vaccinated participants than in unvaccinated ones. In total, 4% and 10% of the unvaccinated population were diagnosed seropositive for the first time while not knowing about the previous infection. Age and gender did not impact antibody titers in high- or low-burden contexts.

Conclusions

Before the Omicron pandemic wave, herd immunity was reached in different contexts in Greece. Higher antibody titers were measured in infected vaccinated individuals than in infected unvaccinated ones.

SUBMITTER: Kotsiou OS

PROVIDER: S-EPMC9140933 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature

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Publications

Lessons We Have Learned Regarding Seroprevalence in High and Low SARS-CoV-2 Contexts in Greece before the Omicron Pandemic Wave.

Kotsiou Ourania S OS Vavougios George D GD Papagiannis Dimitrios D Matsiatsiou Elena E Avgeri Dimitra D Fradelos Evangelos C EC Siachpazidou Dimitra I DI Perlepe Garifallia G Miziou Angeliki A Kyritsis Athanasios A Gogou Eudoxia E Kalampokas Serafim S Kalantzis Georgios G Kotsios Vaios S VS Gourgoulianis Konstantinos I KI

International journal of environmental research and public health 20220517 10

<h4>Background</h4>Antibody seroprevalence in rural communities remains poorly investigated. We compared the SARS-CoV-2 seroprevalence in two Greek communities in June and July 2021 after the end of the Delta-driven pandemic wave that started in November 2020. One community was affected worse than the other.<h4>Methods</h4>The SARS-CoV-2 IgG II Quant method (Architect, Abbott, IL, USA) was used for antibody testing.<h4>Results</h4>We found a high rate of SARS-CoV-2 seropositivity in both communi ...[more]

PMID: 35627648

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Dataset Information

Lessons We Have Learned Regarding Seroprevalence in High and Low SARS-CoV-2 Contexts in Greece before the Omicron Pandemic Wave.

Background

Methods

Results

Conclusions

Publications

Lessons We Have Learned Regarding Seroprevalence in High and Low SARS-CoV-2 Contexts in Greece before the Omicron Pandemic Wave.

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