The Molecular Genetics of Dissociative Symptomatology: A Transdiagnostic Literature Review.

ABSTRACT: Dissociative disorders are a common and frequently undiagnosed group of psychiatric disorders, characterized by disruptions in the normal integration of awareness, personality, emotion and behavior. The available evidence suggests that these disorders arise from an interaction between genetic vulnerability and stress, particularly traumatic stress, but the attention paid to the underlying genetic diatheses has been sparse. In this paper, the existing literature on the molecular genetics of dissociative disorders, as well as of clinically significant dissociative symptoms not reaching the threshold of a disorder, is reviewed comprehensively across clinical and non-clinical samples. Association studies suggest a link between dissociative symptoms and genes related to serotonergic, dopaminerg

SUBMITTER: Rajkumar RP 

PROVIDER: S-EPMC9141026 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature