Toward an observatory of the evolution of clinical trials through phylomemy reconstruction: the COVID-19 vaccines example.

ABSTRACT:

Objectives

To visualize the evolution of all registered COVID-19 vaccine trials.

Study design and setting

As part of the living mapping of the COVID-NMA initiative, we identify biweekly all COVID-19 vaccine trials and automatically extract data from the EU clinical trials registry, ClinicalTrials.gov, IRCT and the World Health Organization International Clinical Trials Registry Platform. Data are curated and enriched by epidemiologists. We have used the phylomemy reconstruction process to visualize the temporal evolution of COVID-19 vaccines trials descriptions. We have analyzed the textual contents of 1,794 trials descriptions (last search in October 2021) and explored their collective structure along with their semantic dynamics.

Results

The structures highlighted b

SUBMITTER: Lobbe Q 

PROVIDER: S-EPMC9142170 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature