Correlation between innate and adaptive immunity response in TB children post BCG vaccination. Is it effective or not?: Cross-sectional study.

ABSTRACT:

Background

How far the role of innate immunity and adaptive immunity do in children who have been BCG vaccinated in controlling the course and the severity of the TB disease has not been completely known. Mycobacterium tuberculosis entry to the body will be recognized by Toll-like receptors found on macrophages, neutrophils, and dendritic cells as part of the innate immune response, after which the dendritic cells will then present the antigen to lymphocyte T0 cells and initiate the adaptive immune response (of which CD4 T cells have an important role in). Was one or were both of these immune responses function well or not in a BCG Vaccinated Children with TB?

Objective

This study aim to find a better understanding of the role of innate immune response assessed by TLR2/TLR4

SUBMITTER: Shabariah R 

PROVIDER: S-EPMC9142374 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature