Demographic, clinical, and radiological characteristics of cleidocranial dysplasia: A systematic review of cases reported in south America.

ABSTRACT:

Introduction

Cleidocranial dysplasia (CCD) is a rare disease characterized by craniofacial, skeletal, and oral anomalies. The disease prevalence is estimated to be 1 per million inhabitants; thus, only a few studies have described large cohorts of CCD patients. This study reviewed the clinical-radiological and demographic characteristics of patients with CCD in South America.

Methods

We conducted a systematic review of all cases of CCD reported in South America following the PRISMA guidelines. Demographic information (sex, age at diagnosis, origin, reason for consultation, and family history) was also recorded. CCD signs were divided into "craniofacial" and "skeletal" categories.

Results

A total of 72 cases were included. We found that oral anomalies were the most com

SUBMITTER: Cano-Perez E 

PROVIDER: S-EPMC9142397 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature