Hair cortisol-a stress marker in children and adolescents with chronic tic disorders? A large European cross-sectional study.

ABSTRACT:

Background

There is clear evidence that tic disorders (TDs) are associated with psychosocial stress as well as emotional and behavioral problems. Studies have shown that individuals with TDs have higher acute physiological stress responses to external, single stressors (as reflected by saliva cortisol). The aim of the present study was to examine a physiological marker of longer-term stress (as reflected by hair cortisol concentration) in children and adolescents with TDs and unaffected siblings of individuals with TDs.

Methods

Two samples of a European cohort were included in this study. In the COURSE sample, 412 children and adolescents aged 3-16 years with a chronic TD including Tourette syndrome according to DSM IV-TR criteria were included. The ONSET sample included 131

SUBMITTER: Buse J 

PROVIDER: S-EPMC9142457 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature