Characterizing the short-latency evoked response to intracortical microstimulation across a multi-electrode array.

ABSTRACT: Objective.Persons with tetraplegia can use brain-machine interfaces to make visually guided reaches with robotic arms. Without somatosensory feedback, these movements will likely be slow and imprecise, like those of persons who retain movement but have lost proprioception. Intracortical microstimulation (ICMS) has promise for providing artificial somatosensory feedback. ICMS that mimics naturally occurring neural activity, may allow afferent interfaces that are more informative and easier to learn than stimulation evoking unnaturalistic activity. To develop such biomimetic stimulation patterns, it is important to characterize the responses of neurons to ICMS.Approach.Using a Utah multi-electrode array, we recorded activity evoked by both single pulses and trains of ICMS at a

SUBMITTER: Sombeck JT 

PROVIDER: S-EPMC9142773 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature