The Detrimental Clinical Associations of Anxiety and Depression with Difficult Asthma Outcomes.

ABSTRACT: Difficult asthma describes asthma in which comorbidities, inadequate treatment, suboptimal inhaler technique and/or poor adherence impede good asthma control. The association of anxiety and depression with difficult asthma outcomes (exacerbations, hospital admissions, asthma control, etc.) is unclear. This study assessed the clinical associations of anxiety and depression with difficult asthma outcomes in patients with a specialist diagnosis of difficult asthma. Using real-world data, we retrospectively phenotyped patients from the Wessex Asthma Cohort of Difficult Asthma (N = 441) using clinical diagnoses of anxiety and depression against those without anxiety or depression (controls). Additionally, we stratified patients by severity of psychological distress using the Hospital Anx

SUBMITTER: Fong WCG 

PROVIDER: S-EPMC9142921 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature