ClusTRace, a bioinformatic pipeline for analyzing clusters in virus phylogenies.

ABSTRACT:

Background

SARS-CoV-2 is the highly transmissible etiologic agent of coronavirus disease 2019 (COVID-19) and has become a global scientific and public health challenge since December 2019. Several new variants of SARS-CoV-2 have emerged globally raising concern about prevention and treatment of COVID-19. Early detection and in-depth analysis of the emerging variants allowing pre-emptive alert and mitigation efforts are thus of paramount importance.

Results

Here we present ClusTRace, a novel bioinformatic pipeline for a fast and scalable analysis of sequence clusters or clades in large viral phylogenies. ClusTRace offers several high-level functionalities including lineage assignment, outlier filtering, aligning, phylogenetic tree reconstruction, cluster extraction, variant c

SUBMITTER: Plyusnin I 

PROVIDER: S-EPMC9143711 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature