Proteomics Studies in Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis.

ABSTRACT: Gestational Diabetes Mellitus (GDM) is the most common metabolic complication during pregnancy and is associated with serious maternal and fetal complications such as pre-eclampsia and stillbirth. Further, women with GDM have approximately 10 times higher risk of diabetes later in life. Children born to mothers with GDM also face a higher risk of childhood obesity and diabetes later in life. Early prediction/diagnosis of GDM leads to early interventions such as diet and lifestyle, which could mitigate the maternal and fetal complications associated with GDM. However, no biomarkers identified to date have been proven to be effective in the prediction/diagnosis of GDM. Proteomic approaches based on mass spectrometry have been applied in various fields of biomedical research to identify novel

SUBMITTER: Sriboonvorakul N 

PROVIDER: S-EPMC9143836 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature