Dataset Information

Effects of Baru Almond Oil (Dipteryx alata Vog.) Treatment on Thrombotic Processes, Platelet Aggregation, and Vascular Function in Aorta Arteries.

ABSTRACT:

Background

This study assessed the effects of Baru (Dipteryx alata Vog.) almond oil supplementation on vascular function, platelet aggregation, and thrombus formation in aorta arteries of Wistar rats.

Methods

Male Wistar rats were allocated into three groups. The control group (n = 6), a Baru group receiving Baru almond oil at 7.2 mL/kg/day (BG 7.2 mL/kg, n = 6), and (iii) a Baru group receiving Baru almond oil at 14.4 mL/kg/day (BG 14.4 mL/kg, n = 6). Baru oil was administered for ten days. Platelet aggregation, thrombus formation, vascular function, and reactive oxygen species production were evaluated at the end of treatment.

Results

Baru oil supplementation reduced platelet aggregation (p < 0.05) and the production of the superoxide anion radical in platelets (p < 0.05). Additionally, Baru oil supplementation exerted an antithrombotic effect (p < 0.05) and improved the vascular function of aorta arteries (p < 0.05).

Conclusion

The findings showed that Baru oil reduced platelet aggregation, reactive oxygen species production, and improved vascular function, suggesting it to be a functional oil with great potential to act as a novel product for preventing and treating cardiovascular disease.

SUBMITTER: Silva-Luis CC

PROVIDER: S-EPMC9143840 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature

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Publications

Effects of Baru Almond Oil (<i>Dipteryx alata Vog.</i>) Treatment on Thrombotic Processes, Platelet Aggregation, and Vascular Function in Aorta Arteries.

Silva-Luis Cristiane Cosmo CC de Brito Alves José Luiz JL de Oliveira Júlio César Pinheiro Lúcio JCPL de Sousa Luis José Alixandre JA Araújo Islania Giselia Albuquerque IGA Tavares Josean Fechine JF do Nascimento Yuri Mangueira YM Bezerra Lorena Soares LS Araújo de Azevedo Fátima de Lourdes Assunção FLA Sobral Marianna Vieira MV Mangueira Vivianne Mendes VM de Medeiros Isac Almeida IA Veras Robson Cavalcante RC

Nutrients 20220518 10

Background: This study assessed the effects of Baru (Dipteryx alata Vog.) almond oil supplementation on vascular function, platelet aggregation, and thrombus formation in aorta arteries of Wistar rats. Methods: Male Wistar rats were allocated into three groups. The control group (n = 6), a Baru group receiving Baru almond oil at 7.2 mL/kg/day (BG 7.2 mL/kg, n = 6), and (iii) a Baru group receiving Baru almond oil at 14.4 mL/kg/day (BG 14.4 mL/kg, n = 6). Baru oil was administered for ten days. P ...[more]

PMID: 35631239

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