A longitudinal resting-state functional connectivity analysis on trauma exposure and post-traumatic stress symptoms in older individuals.

ABSTRACT:

Background

Given the present demographic shift towards an aging society, there is an increased need to investigate the brain's functional connectivity in the context of aging. Trauma exposure and post-traumatic stress disorder (PTSD) symptoms are factors known to impact healthy aging and have been reported to be associated with functional connectivity differences. In the present study, we examined and compared differences in within-default mode network (DMN), within-salience network (SN) and between-DMN-SN functional connectivity, between trauma-exposed individuals with and without PTSD symptoms as well as non-traumatized individuals in a non-clininical older adult sample.

Methods

Resting state functional MRI and behavioral data is taken from the Longitudinal Healthy Aging B

SUBMITTER: Eising CM 

PROVIDER: S-EPMC9144015 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature