Blood Transfusion Reactions-A Comprehensive Review of the Literature including a Swiss Perspective.

ABSTRACT: Blood transfusions have been the cornerstone of life support since the introduction of the ABO classification in the 20th century. The physiologic goal is to restore adequate tissue oxygenation when the demand exceeds the offer. Although it can be a life-saving therapy, blood transfusions can lead to serious adverse effects, and it is essential that physicians remain up to date with the current literature and are aware of the pathophysiology, initial management and risks of each type of transfusion reaction. We aim to provide a structured overview of the pathophysiology, clinical presentation, diagnostic approach and management of acute transfusion reactions based on the literature available in 2022. The numbers of blood transfusions, transfusion reactions and the reporting rate of transfu

SUBMITTER: Ackfeld T 

PROVIDER: S-EPMC9144124 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature