Omicron Infection Evokes Cross-Protection against SARS-CoV-2 Variants in Vaccinees.

ABSTRACT: Due to the rapid global spread of the Omicron (B.1.1.529) variant, efforts to scale up COVID-19 booster vaccination have been improved, especially in light of the increasing evidence of reduced neutralizing antibody (NT Ab) over time in vaccinated subjects. In this study, neutralizing antibody responses against the Wild-Type, Delta, and Omicron strains were evaluated among vaccinees, both infected with Omicron or uninfected, and non-vaccinated subjects infected with Omicron. The aim of the study was to compare the cross-protective humoral response to the variant strains induced by vaccination and/or Omicron infection. The results showed a significant difference in the neutralizing antibody response between the vaccinees and the Omicron-infected vaccinated subjects against the three tested

SUBMITTER: Anichini G 

PROVIDER: S-EPMC9144393 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature