The Combined Value of Type2 Inflammatory Markers in Chronic Obstructive Pulmonary Disease.

ABSTRACT: The roles of type2 inflammatory markers in chronic airway diseases have been assessed in previous studies. However, the relationship between the combined value of these biomarkers and chronic obstructive pulmonary disease (COPD) has not been fully elucidated. We aimed to investigate the roles of the combined value of the fraction of exhaled nitric oxide (FeNO) level and blood eosinophil count in COPD and the predictive capability of these biomarkers. In total, 266 patients were included in our analysis. When the two type2 biomarkers were assessed separately, there were limited correlations between either increased FeNO level or blood eosinophil count and decreased incidence of total exacerbation or frequency of mild exacerbation. Combining these two biomarkers strengthened their associatio

SUBMITTER: Liu Y 

PROVIDER: S-EPMC9144416 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature