Facing the Human and Animal Brucellosis Conundrums: The Forgotten Lessons.

ABSTRACT: Brucellosis is a major zoonotic disease caused by Brucella species. Historically, the disease received over fifty names until it was recognized as a single entity, illustrating its protean manifestations and intricacies, traits that generated conundrums that have remained or re-emerged since they were first described. Here, we examine confusions concerning the clinical picture, serological diagnosis, and incidence of human brucellosis. We also discuss knowledge gaps and prevalent confusions about animal brucellosis, including brucellosis control strategies, the so-called confirmatory tests, and assumptions about the primary-binding assays and DNA detection methods. We describe how doubtfully characterized vaccines have failed to control brucellosis and emphasize how the requisites o

SUBMITTER: Moreno E 

PROVIDER: S-EPMC9144488 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature