A systematic review and meta-analysis of sex differences in cannabis use disorder amongst people with comorbid mental illness.

ABSTRACT:

Background

While males are more likely diagnosed with cannabis use disorder (CUD), females are more susceptible to developing and maintaining CUD. Yet, for both sexes, CUD is associated with high rates of comorbid mental illness (MI).

Objectives

To identify and compare sex differences in the prevalence of comorbid CUD amongst individuals with/without MIs.

Methods

This systematic review generated pooled odds ratios (OR) and 95% confidence intervals (CI) from 37 studies (including clinical trials, cohort, and case-control studies) among individuals with and without MIs, quantifying sex differences in rates of comorbid CUD. A meta-analysis was also completed.

Results

In the CUD-only group, males were twice as likely to have CUD than females (OR = 2.0, CI = 1.9-2.1

SUBMITTER: Kozak K 

PROVIDER: S-EPMC9144491 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature