Paediatric Partial-Thickness Burn Therapy: A Meta-Analysis and Systematic Review of Randomised Controlled Trials.

ABSTRACT:

Background

Paediatric second-degree burn injuries are a significant source of medical challenges to the population that may cause severe, lifelong complications. Currently, there are dozens of therapeutic modalities and we aimed to summarise their reported outcomes and determine their effectiveness, compared to the widely used silver sulphadiazine (SSD).

Methods

We conducted the meta-analysis and systematic review of randomised controlled trials (RCTs), which investigated the performance of dressings in acute paediatric partial-thickness burns. The evaluated endpoints were time until wound closure, grafting and infection rate, number of dressing changes and length of hospitalisation.

Results

Twenty-nine RCTs were included in the qualitative and 25 in the quantitative

SUBMITTER: Lorincz A 

PROVIDER: S-EPMC9144506 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature